Wasps had a disappointing start to their Guinness Premiership title defence as London Irish cruised to a 26-14 win on Saturday.
Back-row prospect Richard Thorpe has signed a three-year contract extension with London Irish.
London Irish have kept the pressure on at the top of Heineken Cup's Pool One after scoring a 41-24 against Newport Gwent Dragons at the Madejski Stadium.
Two debutants will start for the Exiles as they entertain Premiership champions Wasps.